USMLE Step 1 Question of the Day
Quiz-summary
0 of 1 questions completed
Questions:
- 1
Information
USMLE Step 1 Questions
You have already completed the quiz before. Hence you can not start it again.
Quiz is loading...
You must sign in or sign up to start the quiz.
You have to finish following quiz, to start this quiz:
Results
Time has elapsed
You have reached 0 of 0 points, (0)
Categories
- Histology 0%
-
Question:
A 45-year-old man cannot leave home without antacids because he has had severe heartburn with every meal for 10 years. Which of the following is likely to be seen on biopsy of his lower esophagus?
Correct Answer: A. Columnar metaplasia
Barrett’s esophagus is a complication of gastro-esophageal reflux disease (GERD). The lower 2/3 of the esophagus is composed of stratified squamous epithelium. With repeated exposure to caustic gastic acid, tissue in the lower esophagus is replaced with columnar glandular epithelium with goblet cells resembling glandular cells of the intestines that secrete mucin. This process is called metaplasia, in this case columnar.
Hyperplasia is an increase in the number of cells in a tissue region, such as endometrial hyperplasia. Hypertrophy describes enlargement of existing cells, such as in hypertrophic cardiomyopathy. Squamous metaplasia would not occur in the esophagus, where epithelium is normally squamous. Squamous metaplasia can occur in the bladder, cervix, or lungs.
- 1
- Answered
- Review
-
Question 1 of 1
1. Question
Category: HistologyA 45-year-old man cannot leave home without antacids because he has had severe heartburn with every meal for 10 years. Which of the following is likely to be seen on biopsy of his lower esophagus?
Correct
Incorrect