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Question:
A 42 year old male with a past medical history of diabetes mellitus is found during a regular physical to have a BP of 145/85. A repeat BP taken 2 days later shows 143/88. What is the most appropriate initial therapy?
Correct Answer: A. Enalapril
This patient is suffering from hypertension and has a history of diabetes which are indications for treatment. In patients with diabetes and hypertension the first line agent is an ACE inhibitor like enalapril (option A) because it has reno protective effects in addition to its blood pressure reducing qualities.
Furosemide is a diuretic that can be used to treat hypertension but it is not a first line agent.
Hydrochlorothiazide is a first line agent for the treatment of hypertension in non-diabetic patients.
Metoprolol is a B-blocker that is used for the treatment of hypertension but is not a first line treatment. Also, B-blockers are contraindicated in diabetic patients due to it’s potential to mask signs of low blood sugar.
Nifedipine is a Calcium channel blocker that is used in the treatment of hypertension but it is not a first line therapy.
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Category: PharmacologyA 42 year old male with a past medical history of diabetes mellitus is found during a regular physical to have a BP of 145/85. A repeat BP taken 2 days later shows 143/88. What is the most appropriate initial therapy?
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