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Question:
A 32-year-old man is brought to the emergency department because of confusion, wheezing, vomiting, and diarrhea for the past 6 hours. He is sweating and salivating profusely. There is generalized muscle weakness. Which of the following substances is the most likely cause of these findings?
Correct Answer: D. Parathion
This patient has been poisoned by the organophosphate parathion. Organophosphates inhibit acetylcholinesterase (AChE), leading to toxic build-up of acetylcholine (ACh) and resulting in the symptoms listed above. Remember the mnemonic DUMBELS associated with cholinergic toxicity: Defecatioin, Urination, Miosis, Bronchorrhea/Bronchospasm/Bradycardia, Emesis, Lacrimation, Salivation.
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Category: PharmacologyA 32-year-old man is brought to the emergency department because of confusion, wheezing, vomiting, and diarrhea for the past 6 hours. He is sweating and salivating profusely. There is generalized muscle weakness. Which of the following substances is the most likely cause of these findings?
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