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Question:
A newborn develops meningitis. Streptococcus is isolated from the mother’s vagina. The organism agglutinates with antiserum directed against type B surface carbohydrate. The virulence of this organism is related to a bacterial constituent that interferes with which of the following host phagocyte functions?
Correct Answer: C. Ingestion
Group B Streptococci, or more specifically S. agalactiae, occasionally colonize the female reproductive tract and are common causes of neonatal meningitis. The best characterized virulence factors of Group B Streptococci are the capsular polysaccharides, which confer serotype specificity. The capsule provides virulence by inhibiting the deposition of complement components on the surface of the organism and therefore inhibiting ingestion (choice C) by cells of the immune system.
The other answer choices are examples of virulence factors of other organisms, but not Group B Streptococci.
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Category: MicrobiologyA newborn develops meningitis. Streptococcus is isolated from the mother’s vagina. The organism agglutinates with antiserum directed against type B surface carbohydrate. The virulence of this organism is related to a bacterial constituent that interferes with which of the following host phagocyte functions?
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