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Question:
A healthy 35-year-old woman has a cast removed from her leg after 6 weeks of immobilization. Which of the following best characterizes her gastrocnemius muscle at this time?
Correct Answer: C. Decrease in number of myofibrils
Muscle atrophy caused by disuse is usually reversible. It is characterized by a decrease in the density of myofibrils (Answer C) but no change in the overall number of muscle fibers (Answer B). Slow-twitch muscle fibers, fast-twitch fibers and intermediate fibers are differentiated cell types, they do not convert after embryogenesis (Answer A). Long-term exercise causes reactive muscle hypertrophy that may include an increase in mitochondrial content (Answer D). Sarcopenia occurs in old age with failure of satellite cells (Answer E) that help regenerate muscle fibers.
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Category: PhysiologyA healthy 35-year-old woman has a cast removed from her leg after 6 weeks of immobilization. Which of the following best characterizes her gastrocnemius muscle at this time?
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